Best Phosphatidylserine Supplements 2026: Cost per Effective Dose
Top pick for Phosphatidylserine: Doctor's Best Phosphatidylserine (SerinAid) — 100mg phosphatidylserine per 1 capsule, SerinAid® branded raw material (Chemi Nutra, soy-derived, traceable supply chain), $0.25/day.
Registry check · Phosphatidylserine
Does anyone independently verify Phosphatidylserine supplements?
Not one of these 6 products is listed by NSF, USP or Informed Sport as a verified product. Yet 2 of them advertise “third-party testing” without naming the certifier that did it — wording no public registry can confirm or deny. A factory-level claim such as “cGMP” audits the plant, not the Phosphatidylserine bottle you would actually receive.
6 checked against all 5,317 US NSF, USP and Informed Sport listings, 2026-08-25. Full method and limitations.
What 6 Phosphatidylserine labels show
Priced per day, these phosphatidylserine products run $0.25 to $0.80 — a 3.2× gap between the cheapest and dearest phosphatidylserine here, across 6 brands.
All Phosphatidylserine Supplements Compared
| Product | Brand | Dose / Serving | Cost / Day | Certification (as labelled) | Pick | Buy |
|---|---|---|---|---|---|---|
| Doctor's Best Phosphatidylserine (SerinAid) | Doctor's Best | 100mg phosphatidylserine / 1 capsule | $0.25 | SerinAid® branded raw material (Chemi Nutra, soy-derived, traceable supply chain) | Buy | |
| NOW Foods Phosphatidyl Serine 100mg | NOW Foods | 100mg phosphatidylserine / 1 capsule | $0.31 | No third-party PS-content testing disclosed; no branded raw material named | Buy | |
| Double Wood Phosphatidylserine 300mg | Double Wood | 300mg phosphatidylserine / 2 capsules | $0.33 | Non-GMO soy, standardized to 20%, HPLC/ISO-17025 tested per brand site | Buy | |
| Swanson Ultra Sunflower Phosphatidylserine (Sharp-PS Green) | Swanson | 100mg phosphatidylserine / 1 softgel | $0.43 | Sharp-PS® Green branded raw material (sunflower-derived, genuinely soy-free, traceable supply chain) | Buy | |
| Jarrow Formulas PS-100 (Sharp-PS) | Jarrow Formulas | 100mg phosphatidylserine / 1 capsule | $0.55 | Sharp-PS® branded raw material (soy-derived, traceable supply chain) | Buy | |
| Nutricost Phosphatidylserine 400mg (Soy-Free) | Nutricost | 400mg phosphatidylserine / 4 capsules | $0.80 | Labeled soy-free; no third-party PS-content testing disclosed | Buy |
In-Depth Phosphatidylserine Guides
Go deeper on phosphatidylserine — by goal, by form, and what the evidence actually supports:
Our Picks
Lowest Cost: Doctor's Best Phosphatidylserine (SerinAid)
100mg phosphatidylserine per 1 capsule. SerinAid® branded raw material (Chemi Nutra, soy-derived, traceable supply chain). $0.25/day. 120 servings per container at $29.99.
The shelf · Phosphatidylserine
These Phosphatidylserine servings are not comparable to each other
NOW Foods Phosphatidyl Serine 100mg states 100 mg a serving and Nutricost Phosphatidylserine 400mg (Soy-Free) states 400 mg — both occupy one row of the same price column. So Doctor's Best Phosphatidylserine (SerinAid) showing 25¢ a day, the lowest here, may be reporting a smaller serving rather than a better price. Before comparing Doctor's Best Phosphatidylserine (SerinAid) with Nutricost Phosphatidylserine 400mg (Soy-Free), check what each calls a serving.
Method: the 6 Phosphatidylserine products above, compared on label facts — serving size, servings per container, form, price. Not a dosing recommendation.
The evidence · Phosphatidylserine
What the published reviews of Phosphatidylserine concluded
- The Impact of Citicoline/Phosphatidylserine Supplementation on Cognitive Performance and Executive Functions in Mental Disorders: A Systematic Review of Controlled Trials. · Human psychopharmacology, 2026
“Given methodological limitations and high risk of bias, current evidence does not support citicoline or PS-containing compounds as effective cognitive enhancers in mental disorders. Consequently, these agents should be positioned as adjunctive or investigational rather than as evidence-based treatments.”
- Phosphatidylserine enriched with polyunsaturated n-3 fatty acid supplementation for attention-deficit hyperactivity disorder in children and adolescents with epilepsy: A randomized placebo-controlled trial. · Epilepsia open, 2024
“Our study remaining underpowered, no formal conclusion about the effect of Ps-Omega3 could be drawn. However, our data strongly suggested that the PS-Omega 3 formulation used in the current study did not improve ADHD symptoms in children with epilepsy.”
- The effect of phosphatidylserine administration on memory and symptoms of attention-deficit hyperactivity disorder: a randomised, double-blind, placebo-controlled clinical trial. · Journal of human nutrition and dietetics : the official journal of the British Dietetic Association, 2014
“PS significantly improved ADHD symptoms and short-term auditory memory in children. PS supplementation might be a safe and natural nutritional strategy for improving mental performance in young children suffering from ADHD.”
- Effects of a food supplement containing phosphatidylserine on cognitive function in Chinese older adults with mild cognitive impairment: A randomized double-blind, placebo-controlled trial. · Journal of affective disorders, 2025
“This food supplement containing phosphatidylserine could improve different cognitive functions of MCI patients, especially short-term memory, and increase serum n-3 PUFAs and neurotransmitters levels. Serum ALA level might play a mediation role.”
Method: PubMed searched in humans for systematic reviews and randomised trials with Phosphatidylserine in the title; these 4 of the 4 that qualified are shown with the authors’ own conclusion quoted rather than summarised. What it cannot tell you: whether Phosphatidylserine will work for you — each of these reports an average across trials published 2014–2026, and null findings are shown here as readily as positive ones.
How these 6 Phosphatidylserine products were ranked
Not one of these 6 phosphatidylserine products could be confirmed in the NSF, USP or Informed Sport registries, so verification separates none of them and the ranking falls to cost per day at the labelled serving. Commission does not enter it: the rate is the same whichever phosphatidylserine you buy. Full methodology.