Build Your Personal Supplement Stack (Free)
How it works: Tell us your age, sex, current medications, and health goals. Our engine cross-references medication-nutrient depletions, clinical evidence for each goal, and demographic needs to build a personalized supplement stack with specific products, doses, timing, and total daily cost.
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1. Demographics
2. Current Medications
Check all that apply. We'll identify nutrients your medications may deplete.
3. Health Goals
Select up to 5 goals. We'll match each to the supplements with the strongest clinical evidence.
4. Conditions / Diet
Check any that apply. These affect which supplements and forms are appropriate.
5. Upload Bloodwork (Optional)
Coming soon: Upload your bloodwork for personalized deficiency analysis. We'll cross-reference your vitamin D, B12, ferritin, and magnesium levels to refine your stack.
The evidence · Magnesium Glycinate
What the published reviews of Magnesium Glycinate concluded
- Magnesium sulphate and other anticonvulsants for women with pre-eclampsia. · The Cochrane database of systematic reviews, 2010
“Magnesium sulphate more than halves the risk of eclampsia, and probably reduces maternal death. There is no clear effect on outcome after discharge from hospital.”
- The Role and the Effect of Magnesium in Mental Disorders: A Systematic Review. · Nutrients, 2020
“The results are not univocal, both in terms of the plasma levels and of therapeutic effects. However, from the available evidence, it emerged that supplementation with magnesium could be beneficial.”
- Magnesium in Migraine Prophylaxis-Is There an Evidence-Based Rationale? A Systematic Review. · Headache, 2018
“This systematic review provides Grade C (possibly effective) evidence for prevention of migraine with magnesium. Prophylactic treatment of migraine by means of high levels of magnesium dicitrate (600 mg) seems to be a safe and cost efficient strategy in clinical use.”
- Neonatal magnesium sulphate for neuroprotection: A systematic review and meta-analysis. · Developmental medicine and child neurology, 2024
“Given the uncertainty of the current evidence, further robust neonatal magnesium sulphate research is justified. This may include high-quality studies to determine stand-alone effects in LMICs and effects with and after therapeutic hypothermia in high-income countries.”
Method: PubMed searched in humans for systematic reviews and meta-analyses with Magnesium Glycinate in the title; these 4 of the 31 that qualified are shown with the authors’ own conclusion quoted rather than summarised. What it cannot tell you: whether Magnesium Glycinate will work for you — each of these reports an average across trials published 2010–2024, and null findings are shown here as readily as positive ones.
Frequently Asked Questions
What supplements should I take?
The supplements you need depend on your age, sex, medications, diet, and health goals. Common foundations include vitamin D3 (42% of adults are deficient), magnesium (50% don't meet the RDA), and omega-3 (90% of Americans don't eat enough fatty fish). Medication-induced depletions are often overlooked — PPIs deplete 5 nutrients, statins deplete CoQ10, and metformin halves B12 levels. Our stack builder analyzes all of these factors for you.
How do I build a personalized supplement stack?
Start with medication-induced depletions (highest-priority gaps), then layer in health goal support, then apply demographic modifiers. Age 50+ needs more B12 and CoQ10. Women of childbearing age need iron and folate. Our stack builder automates this — enter your profile and get a complete protocol with products, doses, timing, and cost.
Can I take all these supplements together?
Most supplements can be taken together, but some need timing separation. Iron and calcium compete for absorption — take them 2 hours apart. Fat-soluble vitamins (D3, omega-3, CoQ10) absorb best with meals containing fat. Magnesium is best taken before bed. Our stack builder includes a timing protocol telling you exactly when to take each supplement.
How much does a supplement stack cost per day?
A typical 3-5 supplement stack costs $1.50–$4.00 per day using best-value products with third-party quality certification. We normalize costs to clinically-effective daily doses — the amount actually studied in trials — not cost per pill.
Do I need supplements if I eat a healthy diet?
Even with a balanced diet, certain gaps are common: 42% of US adults are vitamin D deficient, 50% don't meet the magnesium RDA through diet, and 90% don't eat enough omega-3 fatty fish. If you take medications like PPIs, statins, metformin, or birth control, you likely have additional depletions that diet alone cannot address.
Related Tools and Guides
- Supplement Recommender — simpler question-based tool
- Supplement Audit Tool — check what you're already taking
- Medication Nutrient Depletion Guide — deep dive on drug-nutrient interactions
- Pre-Built Supplement Stacks — condition-specific protocols
- Our Methodology