Best Glycine Supplements 2026: Cost per Effective Dose
Top pick for Glycine: BulkSupplements Glycine Powder (1 kg) — 3000mg glycine per 1 scoop (3 g), Third-party lab tested, $0.10/day. Our best-value pick.
Registry check · Glycine
Does anyone independently verify Glycine supplements?
Not one of these 8 products is listed by NSF, USP or Informed Sport as a verified product. Yet 5 of them advertise “third-party testing” without naming the certifier that did it — wording no public registry can confirm or deny. A factory-level claim such as “cGMP” audits the plant, not the Glycine bottle you would actually receive.
8 checked against all 5,317 US NSF, USP and Informed Sport listings, 2026-08-25. Full method and limitations.
What 8 Glycine labels show
Priced per day, these glycine products run $0.10 to $1.17 — a 12× gap between the cheapest and dearest glycine here, across 7 brands.
All Glycine Supplements Compared
| Product | Brand | Dose / Serving | Cost / Day | Certification (as labelled) | Pick | Buy |
|---|---|---|---|---|---|---|
| BulkSupplements Glycine Powder (1 kg) | BulkSupplements | 3000mg glycine / 1 scoop (3 g) | $0.10 | Third-party lab tested | Best Value | Buy |
| NOW Foods Glycine Pure Powder (1 lb) | NOW Foods | 3000mg glycine / 3/4 tsp (3 g) | $0.12 | GMP (NPA) | Buy | |
| Nutricost Glycine Powder (1 lb) | Nutricost | 3000mg glycine / 1 scoop (3 g) | $0.15 | Independent lab tested | Buy | |
| NOW Foods Glycine 1000 mg Capsules (100) | NOW Foods | 1000mg glycine / 1 capsule | $0.35 | GMP (NPA) | Buy | |
| Double Wood Glycine 1000 mg (300 capsules) | Double Wood | 1000mg glycine / 2 capsules | $0.40 | Third-party tested | Buy | |
| NutraBio Glycine Powder (150 g) | NutraBio | 1000mg glycine / 1 scoop (1 g) | $0.40 | Fully-disclosed label / COA | Buy | |
| Thorne Glycine (250 capsules) | Thorne | 1000mg glycine / 2 capsules | $0.74 | Third-party certified | Buy | |
| Pure Encapsulations Glycine (180 capsules) | Pure Encapsulations | 1500mg glycine / 3 capsules | $1.17 | NSF-audited GMP, hypoallergenic | Buy |
Our Picks
Best Value: BulkSupplements Glycine Powder (1 kg)
3000mg glycine per 1 scoop (3 g). Third-party lab tested. $0.10/day. 333 servings per container at $32.97.
Dose check · Glycine
Most of these Glycine products need more than one serving to reach the studied dose
The research on Glycine uses 3,000 mg to 5,000 mg (free-form glycine, identical molecule across brands). The products here are labelled from 1,000 mg to 3,000 mg a serving, so the cost of a day at the studied dose is not the price in the table — it is that price multiplied. NOW Foods Glycine 1000 mg Capsules (100) takes 3 servings, which makes a real day 35¢ rather than 12¢.
The label trap on Glycine:a 3g dose is six 500mg capsules — capsules cost far more per gram than bulk powder
Method: studied range from our own Glycine dosage guide (PMID 22529837), priced against the 8 products above — capsules in whole servings, powders in fractions. Trial doses, not a prescription.
The shelf · Glycine
Capsules cost 3.5× what powder does for the same Glycine
The molecule is the same either way; the premium buys encapsulation. Across these 8 Glycine products that gap runs from 10¢ a day (BulkSupplements Glycine Powder (1 kg)) to $1.17 (Pure Encapsulations Glycine (180 capsules)), and BulkSupplements Glycine Powder (1 kg) is the cheapest powder of the 4 here if you will actually weigh a dose.
Method: the 8 Glycine products above, compared on label facts — serving size, servings per container, form, price. Not a dosing recommendation.
The evidence · Glycine
What the published reviews of Glycine concluded
- Supplementing Glycine and N-Acetylcysteine (GlyNAC) in Older Adults Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Physical Function, and Aging Hallmarks: A Randomized Clinical Trial. · The journals of gerontology. Series A, Biological sciences and medical sciences, 2023
“GlyNAC supplementation in OA for 16-weeks was safe and well-tolerated. By combining the benefits of glycine, NAC and GSH, GlyNAC is an effective nutritional supplement that improves and reverses multiple age-associated abnormalities to promote health in aging humans.”
- Effect of oral glycine on the clinical, spirometric and inflammatory status in subjects with cystic fibrosis: a pilot randomized trial. · BMC pulmonary medicine, 2017
“The clinical, spirometric and inflammatory status of subjects with CF improved after just 8 weeks of glycine intake, suggesting that this amino acid might constitute a novel therapeutic tool for these patients.”
- The effect of enteral glycine on plasma glycine and muscle structure, size, and function in the critically ill: A randomized controlled trial. · Clinical nutrition (Edinburgh, Scotland), 2025
“In critically ill patients, glycine supplementation increases plasma and muscle glycine concentrations and the effect of glycine on muscle loss warrants further evaluation in larger studies.”
Method: PubMed searched in humans for randomised trials with Glycine in the title; these 3 of the 3 that qualified are shown with the authors’ own conclusion quoted rather than summarised. What it cannot tell you: whether Glycine will work for you — each of these reports an average across trials published 2017–2025, and null findings are shown here as readily as positive ones.
How these 8 Glycine products were ranked
Not one of these 8 glycine products could be confirmed in the NSF, USP or Informed Sport registries, so verification separates none of them and the ranking falls to cost per day at the labelled serving. Commission does not enter it: the rate is the same whichever glycine you buy. Full methodology.