Cranberry Supplements: The PAC Number That Isn't on the Label
Cranberry pills can lower the chance of another UTI for some people, mainly women who get them often. What counts is PAC, a cranberry compound: trials at 36 mg a day or more cut UTI risk by about 18%. Most labels do not state it. Our pick: TheraCran One, 36 mg in one capsule, $1.20 a day.
By Erin Rose Updated October 18, 2026 How we score
Costs are brand prices per 36 mg of PAC (October 18, 2026).
What to buy
Theralogix TheraCran One is our pick. Each capsule states 36 mg of PAC, and it is on NSF/ANSI 173, a public testing list that checks the capsule holds what the label says.
Theralogix TheraCran One
36 mg PAC · $1.20 a day
Want D-mannose in the same pill? TheraCran Max adds 1,000 mg of D-mannose to 40 mg of PAC in 2 capsules, on the same NSF list.
Theralogix TheraCran Max
40 mg PAC + D-mannose · $1.34 a day
Where to go next
- Best cranberry supplement: the products we compared, ranked.
- Cranberry dosage guide: how much PAC to take.
What cranberry does
Cranberries hold PAC (A-type proanthocyanidins). In lab tests of urine, PAC kept E. coli, the usual cause of bladder infections, from sticking to cells (Howell 2010). That is the main idea behind taking cranberry for UTIs.
| Who | Evidence | What trials found |
|---|---|---|
| Women who get UTIs often | Moderate | A Cochrane review found fewer repeat UTIs with cranberry products. |
| Children | Moderate | The same review found fewer UTIs in children. |
| After medical procedures | Moderate | Fewer UTIs in people at risk after procedures, in the same review. |
| Any adult, by dose | Some | A 2024 review found trials at 36 mg of PAC a day or more cut UTI risk by about 18%; lower doses showed no clear drop. |
| Older women in nursing homes | Little or none | A year-long trial in JAMA found no drop in bacteria and white cells in the urine, and about the same number of UTIs. |
| Pregnancy; bladder that does not empty | Little or none | The Cochrane review found little or no benefit in these groups. |
Why most labels do not tell you the dose
Only 3 of the 12 cranberry products we checked print a PAC number on the label (Utiva puts 36 mg in its name). The rest give milligrams of cranberry, “Pacran,” or “equal to 25,000 mg of fruit.” Those numbers describe fruit weight, not PAC, so a bigger one does not mean more PAC. Look for “PAC” followed by milligrams.
How long does it take?
Months, not days. The trials in the 2024 review that found a benefit gave cranberry daily for 12 to 24 weeks (Xiong 2024). In a 6-month trial of healthy women with repeat UTIs, about 37 mg of PAC a day cut UTIs by 24% compared with about 2 mg, but the difference could have been chance (Babar 2021).
How much to take
At least 36 mg of PAC a day, one capsule of our pick. The dosage guide has a calculator.
Is cranberry safe?
For most people, yes. A few things to check:
- UTI symptoms now: see a doctor. Cranberry does not treat an infection.
- Warfarin: ask your doctor before taking cranberry.
- Kidney stones: ask your doctor, since concentrated cranberry may not suit people who form stones.
Questions people ask
Does cranberry treat a UTI?
No. Cranberry was studied for lowering the chance of the next UTI, not for treating one you have. If you have symptoms, see a doctor; an infection may need antibiotics.
Is cranberry juice enough?
Juice has sugar and an unknown amount of PAC. A capsule that states 36 mg of PAC is the simplest way to know what you get. See the best cranberry supplements.
Sources
- Williams G, et al. “Cranberries for preventing urinary tract infections.” Cochrane Database Syst Rev. 2023. PubMed 37068952
- Xiong Z, et al. “Cranberry supplementation for the prevention of urinary tract infections: a meta-analysis.” Front Nutr. 2024. PubMed 39668896
- Howell AB, et al. “Dosage effect on uropathogenic Escherichia coli anti-adhesion activity in urine following consumption of cranberry powder standardized for proanthocyanidin content.” BMC Infect Dis. 2010. PubMed 20398248
- Juthani-Mehta M, et al. “Effect of Cranberry Capsules on Bacteriuria Plus Pyuria Among Older Women in Nursing Homes: A Randomized Clinical Trial.” JAMA. 2016. PubMed 27787564
- Babar A, et al. “High dose versus low dose standardized cranberry proanthocyanidin extract for the prevention of recurrent urinary tract infection in healthy women.” BMC Urol. 2021. PubMed 33757474